ALLERGIES AND THE THREE OPTIONS
This is not our allergy page- just a very basic starter page before it is launched to understand our 3 options.
All our page and information is copy righted .
We have three options to assist with allergies .
1) laboratory tested kittens THE GOLD STANDARD
2) Home sittings THE SILVER STANDARD
3) Fur samples THE BRONZE STANDARD
Silver and Bronze services are offered to everyone even if you are not adopting from us.
If you would like to adopt from us we require you order a fur samples as a minimum .
We do recommend a sitting and backed up with fur samples or for the gold standard of security laboratory tested kitten .
We require fur samples to be ordered as a minuimin to protect each party and to minimise the return the kittens . It is a good tool at assessing your own allergies.
We understand home sittings due to covid 19 isn’t always possible, but we are willing to hold sittings when restrictions ease.
We have 15 years experience with allergies with fur samples and sittings , and the First UK cattery to start offering fur samples in the UK in siberians .
In the UK todate we are the First and only UK cattery to be testing the FELD1 and FELD4 with such extensive studies and data to back up all our claims .
We have two years of kitten placements for level 3 4 to 5 and 100% success rate to date.
We are proud to continue to help families and owners to have a special companion in their life .
Within our studies we have worked with all levels and extensively with severe and chronic asthma sufferers and also children with excellent success .
Are siberians really Hypoallergenic ?
We decided that over two years ago to find out the truth just like you may of …. we had heard so many stories in our 15 years breeding, different ways and information.
Every breeder has different take on things and contradictions … So we asked ourselves what’s the truth here when no one had any proof or studies themselves or done any testing in the UK ?
We have found from our own studies that most if not all information out there is incorrect to an extent or with falsehoods and or with misleading information at best .
All our kings and queens have been FELD4 tested and our young females have been FELD1 Tested and we have started to hold back level 4-5 queens and kings for our own breeding program.
We offer a FELD1 tested siberian kitten which can leave at 14 weeks and we can offer the FELD4 fur testing alongside the FELD1 .
What causes allergies?
There are many myths and misconceptions related to cat allergens and many people who suffer from cat allergies do not fully understand the actual cause of their allergy.
What is an allergic reaction
Pathophysiology
immunoglobulin E (IgE) meaning is antibodies produced by the immune system. If you have an allergy, your immune system overreacts to an allergen by producing antibodies called Immunoglobulin E (IgE). These antibodies travel to cells that release chemicals, causing an allergic reaction.
As the allergen enters through the nose or mouth, antigen cells analyze the allergen and present antigenic peptides to helper T cells The helper T cells acquire a type 2 phenotype (Th2) and produce IgE due to the presence of specific cytokines. If Th2 is expressed too much, the symptoms of cat allergies appear. Inhaled cat allergens will activate mast cells, causing coughing, increased mucus production, and airway constriction.
Cat allergens have significant allergenicity. They are also numerous and cat allergen extracts are therefore a multi-allergenic source. 10 allergens have been identified in studies of extracts from fur, saliva, serum and urine
anti-Fel d 1 specific IgE is found in the serum of more than 80–98% of patients allergic to cats.
Eight cat allergens have been registered to date (Fel d 1 to Feld d 8)
The most important cat allergen in disease pathogenesis is, unlike in other mammals, a secretoglobin, called Fel d 1.
Fel d 1 is easily airborne and remains in the indoor environment for up to 6 months after the cat is removed .
FELD1 is responsible for over 80% of reactions .
What is Feld1?
fel d 1 is a secretoglobin protein that, in cats, is encoded by the CH1 (chain 1/Fel d 1-A) and CH2 (chain 2/Fel d 1-B) genes.Among cats, Fel d 1 is produced largely in their saliva and by the sebaceous glands located in their skin. It is the primary allergen present on cats and kittens. The function of the protein for cats is unknown, but it causes an IgG or IgE reaction in sensitive humans (either as an allergic or asthmatic response).
Kittens produce less Fel d 1 than adult cats. Female cats produce a lower level of Fel d 1 than (unneutered) males,while neutered males produce levels similar to those of females. Both intact and spayed females produce similar levels.
Although females and neutered males produce Fel d 1 in lower levels, they still produce enough to cause allergic symptoms in sensitive individuals.
We have designed specialist testing to determine the real level of a kittens and cats hypoallergenic level regardless of ageing and sex.
WHY ARE SIBERIANS THE PERFECT BREED FOR ALLERGIES.
Siberian breed, native to the Siberian region for which the breed is named, have been shown to have genetic variants that result in a lower production of Fel d 1.
Siberians compared to all other cat breeds have up to a 50% lower allergen level which is a big plus point for Siberians and assists with higher success stories among suffers.
The Siberian Cat produces a lower level of FEL D1, due to a protein sequence missing from their DNA. Only pure-bred pedigree Siberian cats will have this genetic advantage.
Meaning the hypoallergenic cat DOES exist, it’s just finding that needle in the haystack.
allergies to cats are one of the most common allergies among individuals. Among the eight known cat allergens, the most prominent allergen is secretoglobin Fel d 1, and it is produced in the anal glands, salivary glands, and, mainly, in sebaceous glands of cats, Allergic symptoms associated with cats include coughing, wheezing, chest tightening, itching, nasal congestion, rash, watering eyes, sneezing, chapped lips, and similar symptoms. In worst-case scenarios, allergies to cats can develop into more life-threatening conditions such as rhinitis and mild to severe forms of asthma. Despite these symptoms, there are many types of solutions to mitigate the allergic effects of cats, including medications, vaccines, and home remedies. Hypoallergenic cats are another solution for individuals who want pets without the allergic consequences. Furthermore, prospective pet owners can reduce allergic reactions by selecting cats such as the siberian which are associated with a lower production of allergens.
The secretion and production of the Fel d1 allergen is often controlled by stress and hormones and changes to hormones.
ARE SIBERIANS REALLY HYPOALLERGENIC
YES
THE HYPOALLERGENIC CAT DOES EXIST.
HOWEVER EVERY KITTEN AND CAT HAS A DIFFERENT LEVEL,
Simplified version some will be hypoallergenic yes , however with out testing it is a lottery to know which is low level or high level and how hypoallergenic a cat or kitten truly is to suit your allergie level.
Siberians compared to all other cat breeds have up to a 50% lower allergen level which is a big plus point for Siberians and assists with higher success stories among suffers.
The Siberian Cat produces a lower level of FEL D1, due to a protein sequence missing from their DNA. Only pure-bred pedigree Siberian cats will have this genetic advantage.
The domestic cat is the most common source for the most inhiladed allergens and affects up to 20% of the population and is often associated with asthma.
FELD1 is the main coarse of all reactions up to 80% of reactions.
FELD2 is responsible for up to 15% of reactions
Serum albumin, often referred to simply as blood albumin, is an albumin found in vertebrate blood. Human serum albumin is encoded by the ALB gene. Other mammalian forms, such as bovine serum albumin, are chemically similar.
Many people if they have additional allergies to rabbits, dogs or horses certain meats such as pork meat could be more sensitive to Siberians and still be triggered by feld1 . there are Over 14 additional substances that can cause allergic reactions have been identified in all mammals,
FELD4 up to 20%
Fel d 4 is a lipocalin allergen produced by the cat, which binds IgE at relatively high frequency in cat-sensitive individuals. The allergen provides not only a means for investigating differences in the immune response to lipocalin allergens from that found for other mammalian species but also an important reagent for the diagnosis of cat allergy.
Fel d 4 and Fel d 7
Fel d 4 and Fel d 7 are cat lipocalins. Fel d 4 and Fel d 7 are one of the most common cat allergens after Fel d 1. Fel d 4 is produced in the submandibular salivary glands and secreted into the saliva of cats, via which it is deposited on to cat dander during grooming, and is associated with atopic dermatitis in children with cat allergies.
INCORRECT WAYS TO ASSES ALLERGIES
In the UK and Europe there are many incorrect ways of assessing people’s allergies and strong statements out there from breeders saying for example a sitting with a neutered retired male is a reliable and effective way to assess one’s allergies.
This is highly incorrect and pointless exercise to do and will still be like a lottery when you take your kitten or cats home.
Many breeders only work with mild allergies only, to why they will have only good success stories and make strong statements that sittings have always worked this way… As we said we have a very good success rate with mild only and would have a near enough 100% success rate just working with this level only.
The reality is a lot of people have more than mild allergies .
There is a big difference between mild to medium to severe allergies which we work with to try and help everyone with allergies not just the easy cases.
We know of stories of large deposits been lost on return of the kittens which could be avoided with better knowledge and understanding off allergies .
Alot of breeders choose not to work with allergies as it is very complex and
This is just one example we do not recommended to do as it has no reliability or credibility to do and could result in a false sense of security if you are not allergic when in fact you very well could be.
A neutered male can have a lower FELD1 ( in depth info to come on our allergie page) and the male could also just be a low allergen siberian.
Again it has no relevance on the kitten you are going to get and you could be testing your allergies with a low allergen level siberian .. and worse it is not a parent to have any genetic influence over if any litters of kittens .
So this is the number one wrong way to asses allergies among with other examples.
However , we have had 15 years of good success with fur samples and home sittings and generally all mild suffers are completely fine with all siberians which is excellent we just double check for caution with fur samples or sitting .
THIS IS WHY FOR US TO ADOPT TO YOU WE REQUIRE YOU TRY AT MINIMUM FUR SAMPLES.
OUR LABORATORY TESTING.
Please be aware of the information you read online of previous studies testing and data as this is NOT what we have done or do.
These are all with the OLD testing kits and has NO relevance to our studies and data in any way shape or form .
A Lot of miss information and false holds online from breeders thinking this is what the testing is as they do not know what we do.
Important to understand not everything online is factual or correct regardless to ones other expertise .
ALLERGIES is in its self its own expertise and is a separate subject to breeding completely .
